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Article

miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels

13 Sept 2018

Abstract excerpt

Follicular lymphoma (FL) is a common indolent B-cell malignancy with a variable clinical course. An unfavorable event in its course is histological transformation to a high-grade lymphoma, typically diffuse large B-cell lymphoma. Recent studies show that genetic aberrations of MYC or its overexpression are associated with FL transformation (tFL). However, the precise molecular mechanisms underlying tFL are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30213873
DOI: 10.1182/blood-2018-06-855502

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