Article
Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.
PloS one - 1 Jan 2018
O'Beirne Sarah L, Salit Jacqueline, Rodriguez-Flores Juan L, Staudt Michelle R, Abi Khalil Charbel, Fakhro Khalid A, Robay Amal, Ramstetter Monica D, Malek Joel A, Zirie Mahmoud, Jayyousi Amin, Badii Ramin, Al-Nabet Al-Marri Ajayeb, Bener Abdulbari, Mahmoud Mai, Chiuchiolo Maria J, Al-Shakaki Alya, Chidiac Omar, Stadler Dora, Mezey Jason G, Crystal Ronald G
Abstract excerpt
BACKGROUND: Type 2 diabetes (T2D) susceptibility is influenced by genetic and lifestyle factors. To date, the majority of genetic studies of T2D have been in populations of European and Asian descent. The focus of this study is on genetic variations underlying T2D in Qataris, a population with one of the highest incidences of T2D worldwide. RESULTS: Illumina HiSeq exome sequencing was performed on 864 Qatari...
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