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Article

Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus.

BMC medical genomics - 29 Apr 2024

Elashi Asma A, Toor Salman M, Umlai Umm-Kulthum Ismail, Al-Sarraj Yasser A, Taheri Shahrad, Suhre Karsten, Abou-Samra Abdul Badi, Albagha Omar M E

Abstract excerpt

BACKGROUND: The genetic basis of type 2 diabetes (T2D) is under-investigated in the Middle East, despite the rapidly growing disease prevalence. We aimed to define the genetic determinants of T2D in Qatar. METHODS: Using whole genome sequencing of 11,436 participants (2765 T2D cases and 8671 controls) from the population-based Qatar Biobank (QBB), we conducted a genome-wide association study (GWAS) of T2D with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38685053
DOI: 10.1186/s12920-024-01855-1
PMCID: PMC11059680

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