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Article

Lifestyle chemical carcinogens associated with mutations in cell cycle regulatory genes increases the susceptibility to gastric cancer risk.

Environmental science and pollution research international - 1 Nov 2018

Yadav Ravi Prakash, Ghatak Souvik, Chakraborty Payel, Lalrohlui Freda, Kannan Ravi, Kumar Rajeev, Pautu Jeremy L, Zomingthanga John, Chenkual Saia, Muthukumaran Rajendra, Senthil Kumar Nachimuthu

Abstract excerpt

In the present study, we correlated the various lifestyle habits and their associated mutations in cell cycle (P21 and MDM2) and DNA damage repair (MLH1) genes to investigate their role in gastric cancer (GC). Multifactor dimensionality reduction (MDR) analysis revealed the two-factor model of oral snuff and smoked meat as the significant model for GC risk. The interaction analysis between identified mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30209766
DOI: 10.1007/s11356-018-3080-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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