Article
Association of polymorphisms at HORMAD2 and prognosis in advanced non-small-cell lung cancer patients.
Cancer epidemiology - 1 Aug 2014
Zhang Kai, Tang Shaowen, Cao Songyu, Hu Lingmin, Pan Yun, Ma Hongxia, Guo Xuejiang, Wu Shuangshuang, Shen Hongbing, Hu Zhibin
Abstract excerpt
BACKGROUND: Cancer-testis (CT) genes are predominantly expressed in the testis and are ectopically activated in a wide range of cancers. The expression of CT antigens has been shown to significantly affect the survival of patients with non-small-cell lung cancer (NSCLC). Recently, a genome-wide association study (GWAS) and expression analysis have identified a novel CT gene (HORMAD2) associated with lung cancer...
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