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Article

Quercetin preferentially induces apoptosis in KRAS-mutant colorectal cancer cells via JNK signaling pathways.

Cell biology international - 1 Feb 2019

Yang Yiwen, Wang Tao, Chen Degao, Ma Qizhao, Zheng Yanjiang, Liao Shiping, Wang Yufang, Zhang Ji

Abstract excerpt

Colorectal cancer (CRC) is the third most common type of cancer, and its incidence and mortality are markedly increasing worldwide. Oncogenic mutations of KRAS occur in up to 40% of CRC cases and pose a great challenge in the treatment of the disease. Quercetin is a dietary flavonoid that exerts anti-oxidant, anti-inflammatory, and anti-cancer properties. The current study investigated the anti-proliferative...

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Identifiers

PMID: 30203888
DOI: 10.1002/cbin.11055
PMCID: PMC13397398

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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