Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.

Molecular and cellular biochemistry - 1 May 2018

Okamoto Haruna, Matsukawa Taiji, Doi Satoshi, Tsunoda Toshiyuki, Sawata Yuuga, Naemura Madoka, Ohnuki Koichiro, Shirasawa Senji, Kotake Yojiro

Abstract excerpt

Resveratrol is a polyphenolic compound in many edible foods including grapes, peanuts, and berries. Several studies have revealed the beneficial effects of resveratrol against various diseases such as heart disease, diabetes, obesity, neurological disorders, and cancer. A recent study showed that resveratrol inhibits the proliferation of HCT116 human colorectal cancer cells in three-dimensional culture (3DC) via...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MCF-7 Cells

Share to Mutation

Share to Proto-Oncogene Proteins p21(ras)

Share to Resveratrol

Share to Signal Transduction

Share to Stilbenes

Source

Identifiers

PMID: 28936721
DOI: 10.1007/s11010-017-3191-x

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.PMID 28936721Read ↗

Cytotoxic Effect of Resveratrol on Colorectal Cancer Cell LineSemantic proximity Read ↗

New Hybrids Based on Curcumin and Resveratrol: Synthesis, Cytotoxicity and Antiproliferative Activity against Colorectal Cancer CellsSemantic proximity Read ↗

Quercetin preferentially induces apoptosis in KRAS-mutant colorectal cancer cells via JNK signaling pathways.Semantic proximity Read ↗

Colorectal cancer chemoprevention by trans-resveratrol.Semantic proximity Read ↗

Grape Seed Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Carcinoma CellsSemantic proximity Read ↗

Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapseSemantic proximity Read ↗

Noncoding RNAs as Molecular Targets of Resveratrol Underlying Its Anticancer EffectsSemantic proximity Read ↗

Regulating miRNAs Expression by Resveratrol: Novel Insights based on Molecular Mechanism and Strategies for Cancer TherapySemantic proximity Read ↗

The Effect of 4′-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell LinesSemantic proximity Read ↗

Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cellsSemantic proximity Read ↗

Chiaurinib Selectively Inhibits Colorectal Cancer with KRAS Wild-Type by Modulation of ROS through Activating the p53 Signaling PathwaySemantic proximity Read ↗

Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.