Correlation between molecular analysis, diagnosis according to the 2015 WHO classification of unresected lung tumours and TTF1 expression in small biopsies and cytology specimens from 344 non-small cell lung carcinoma patients.

doi:10.1016/j.pathol.2017.07.002

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Article

Correlation between molecular analysis, diagnosis according to the 2015 WHO classification of unresected lung tumours and TTF1 expression in small biopsies and cytology specimens from 344 non-small cell lung carcinoma patients.

Pathology - 1 Oct 2017

Russell Prudence A, Rogers Toni-Maree, Solomon Benjamin, Alam Naveed, Barnett Stephen A, Rathi Vivek, Williams Richard A, Wright Gavin M, Conron Matthew

Abstract excerpt

We investigated correlations between diagnosis according to the 2015 World Health Organization (WHO) classification of unresected lung tumours, molecular analysis and TTF1 expression in small biopsy and cytology specimens from 344 non-small cell lung carcinoma (NSCLC) patients. One case failed testing for EGFR, KRAS and ALK abnormalities and six had insufficient tumour for ALK testing. Overall mutation rate in...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Australia
Biopsy
Carcinoma, Non-Small-Cell Lung
DNA-Binding Proteins
Female
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunohistochemistry

Lung Neoplasms

Male

Middle Aged

Mutation

Transcription Factors

World Health Organization

Source

Open in PubMed

Identifiers

PMID: 28811082
DOI: 10.1016/j.pathol.2017.07.002

Genes

ALK
KRAS
EGFR
TTF1
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28811082-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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