Article
Detection of a novel aph(2") allele (aph[2"]-Ie) conferring high-level gentamicin resistance and a spectinomycin resistance gene ant(9)-Ia (aad 9) in clinical isolates of enterococci.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2005
Mahbub Alam Mohammed, Kobayashi Nobumichi, Ishino Masaho, Sumi Ayako, Kobayashi Ken-Ichiro, Uehara Nobuyuki, Watanabe Naoki
Abstract excerpt
Aminoglycoside-modifying enzymes (AMEs) are major factors that confer aminoglycoside resistance to enterococci. In an epidemiologic study on distribution of 12 AME genes in 534 recent clinical strains isolated from a Japanese hospital, two uncommon AME genes, ant(9)-Ia and a novel aph(2") allele, aph(2")-Ie, were detected. ant(9)-Ia had been reported only in Staphylococcus aureus and encodes spectinomycin...
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