Article
Genetic diversity of enterococci harboring the high-level gentamicin resistance gene aac(6')-Ie-aph(2'')-Ia or aph(2'')-Ie in a Japanese hospital.
Microbial drug resistance (Larchmont, N.Y.) - 1 Sept 2009
Watanabe Shojiro, Kobayashi Nobumichi, Quiñones Dianelys, Nagashima Shigeo, Uehara Nobuyuki, Watanabe Naoki
Abstract excerpt
Prevalence of high-level gentamicin resistance genes aac(6')-Ie-aph(2'')-Ia and aph(2'')-Ie, which encode distinct aminoglycoside-modifying enzymes, was analyzed for a total of 1128 clinical isolates of enterococci obtained in a Japanese hospital during a period between 1997 and 2007. The aac(6')-Ie-aph(2'')-Ia was detected in 40.1%, 12.9%, and 3.6% of Enterococcus faecalis, E. faecium, and other enterococcal...
Topics
- Acetyltransferases
- Aminoglycosides
- Anti-Bacterial Agents
- DNA Transposable Elements
- Drug Resistance, Bacterial
- Enterococcus
- Enterococcus faecalis
- Enterococcus faecium
- Genetic Variation
- Gentamicins