Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization

8 Sept 2018

Abstract excerpt

Pathological observations show that cancer cells frequently invade the surrounding stroma in collective groups rather than through single cell migration. Here, we studied the role of the actin-binding protein Girdin, a specific regulator of collective migration of neuroblasts in the brain, in collective cancer cell migration. We found that Girdin was essential for the collective migration of the skin cancer cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Caveolin-1 and cellular processes
Share to Cell Adhesion Molecules Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30194792
DOI: 10.1111/cas.13795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organizationPMID 30194792Read ↗

Collective invasion of cancer: Perspectives from pathology and developmentSemantic proximity Read ↗

Collective cell migration: Implications for wound healing and cancer invasionSemantic proximity Read ↗

Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer CellsSemantic proximity Read ↗

A <i>Drosophila</i> RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migrationSemantic proximity Read ↗

Using Zebrafish to Study Collective Cell Migration in Development and DiseaseSemantic proximity Read ↗

Expression and structural features of endoglin (CD105), a transforming growth factor β1 and β3 binding protein, in human melanomaSemantic proximity Read ↗

Regulation of Cell Adhesion and Collective Cell Migration by Hindsight and Its Human Homolog RREB1Semantic proximity Read ↗

GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer CellsSemantic proximity Read ↗

Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration.Semantic proximity Read ↗

Interplay between cadherins and α2β1 integrin differentially regulates melanoma cell invasionSemantic proximity Read ↗

Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migrationSemantic proximity Read ↗

Transgelins, cytoskeletal proteins implicated in different aspects of cancer developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.