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Collective invasion of cancer: Perspectives from pathology and development

21 Feb 2016

Abstract excerpt

Clinical pathologists have long been aware that in many types of human malignant tumors, the cells are often connected and form groups of various sizes or "nests". In this way, they achieve "collective invasion" into the surrounding stroma, rather than spreading out individually. Such collective behavior is also a common feature of migration during embryonic and postnatal developmental stages, suggesting there...

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PMID: 26897041
DOI: 10.1111/pin.12391

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