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Article

Inflammatory markers of CHMP2B-mediated frontotemporal dementia.

Journal of neuroimmunology - 15 Nov 2018

Roos Peter, von Essen Marina Rode, Nielsen Troels Tolstrup, Johannsen Peter, Stokholm Jette, Bie Anne Sigaard, Waldemar Gunhild, Simonsen Anja Hviid, Heslegrave Amanda, Zetterberg Henrik, Sellebjerg Finn, Nielsen Jørgen Erik

Abstract excerpt

Histopathological studies and animal models have suggested an inflammatory component in the pathomechanism of the CHMP2B associated frontotemporal dementia (FTD-3). In this cross-sectional study, serum and cerebrospinal fluid were analyzed for inflammatory markers in CHMP2B mutation carriers. Serum levels of CCL4 were increased throughout life. Serum levels of IL-15, CXCL10, CCL22 and TNF-α were significantly...

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Identifiers

PMID: 30193769
DOI: 10.1016/j.jneuroim.2018.08.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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