Article
Genetic Determinants of Telomere Length in African American Youth.
Scientific reports - 5 Sept 2018
Zeiger Andrew M, White Marquitta J, Eng Celeste, Oh Sam S, Witonsky Jonathan, Goddard Pagé C, Contreras Maria G, Elhawary Jennifer R, Hu Donglei, Mak Angel C Y, Lee Eunice Y, Keys Kevin L, Samedy Lesly-Anne, Risse-Adams Oona, Magaña Joaquín, Huntsman Scott, Salazar Sandra, Davis Adam, Meade Kelley, Brigino-Buenaventura Emerita, LeNoir Michael A, Farber Harold J, Bibbins-Domingo Kirsten, Borrell Luisa N, Burchard Esteban G
Abstract excerpt
Telomere length (TL) is associated with numerous disease states and is affected by genetic and environmental factors. However, TL has been mostly studied in adult populations of European or Asian ancestry. These studies have identified 34 TL-associated genetic variants recently used as genetic proxies for TL. The generalizability of these associations to pediatric populations and racially diverse populations,...
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