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Article

The ECM as a driver of heart development and repair

1 Mar 2021

Abstract excerpt

The developing heart is formed of two tissue layers separated by an extracellular matrix (ECM) that provides chemical and physical signals to cardiac cells. While deposition of specific ECM components creates matrix diversity, the cardiac ECM is also dynamic, with modification and degradation playing important roles in ECM maturation and function. In this Review, we discuss the spatiotemporal changes in ECM...

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PMID: 33674261
DOI: 10.1242/dev.191320

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