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Article

Factors Predicting the Therapeutic Response to Methotrexate in Japanese Patients with Rheumatoid Arthritis: A Hospital-Based Cohort Study.

Biological & pharmaceutical bulletin - 1 Jan 2018

Hakamata Jun, Kaneko Yuko, Shimizu Mikiko, Yamaoka Kunihiro, Maruyama Junya, Takeuchi Tsutomu, Mochizuki Mayumi, Hashiguchi Masayuki

Abstract excerpt

Methotrexate (MTX) is used widely as a first-line drug for the treatment of rheumatoid arthritis (RA) worldwide. There are large interindividual differences in the therapeutic response to MTX, but it is not known which factors influence them. We therefore investigated predictive factors associated with the therapeutic response to MTX in a hospital-based cohort study. Japanese adult RA outpatients prescribed MTX...

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PMID: 30175777
DOI: 10.1248/bpb.b18-00247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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