Article
Cortical surface area correlates with STON2 gene Ser307Pro polymorphism in first-episode treatment-naïve patients with schizophrenia.
PloS one - 1 Jan 2013
Xiang Bo, Wu Jun-Yao, Wang Qiang, Li Ming-Li, Jiang Li-Jun, Deng Wei, Chen Zhuang-Fei, He Zong-Ling, Huang Cao-Hua, Han Yuan-Yuan, Li Yin-Fei, Lin Yin, Liu Xiang, Wang Ying-Cheng, Ma Xiao-Hong, Gong Qi-Yong, Li Tao, Hu Xun
Abstract excerpt
BACKGROUND: Evidence shows that STON2 gene is associated with synaptic function and schizophrenia. This study aims to explore the relationship between two functional polymorphisms (Ser307Pro and Ala851Ser) of STON2 gene and the cortical surface area in first-episode treatment-naïve patients with schizophrenia and healthy controls. METHODOLOGY/PRINCIPAL FINDINGS: Magnetic resonance imaging of the whole cortical...
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