Article
Association between PTCH1 and RAD54B single-nucleotide polymorphisms and non-syndromic orofacial clefts in a northern Chinese population.
The journal of gene medicine - 1 Dec 2018
Liu Xiaotong, Yang Shaoyou, Meng Lingwei, Chen Chunyu, Hui Xiang, Jiang Yuxin, Jiao Xiaohui, Lv Kewen, Song Tao
Abstract excerpt
BACKGROUND: Non-syndromic orofacial clefts (NSOC) is one of the most common congenital malformations, and its etiology involves both genetic and environmental factors. The present aimed to investigate the association of six single nucleotide polymorphisms (SNPs) (rs10512248 in PTCH1, rs12681366 and rs958447 in RAD54B, rs13317 in FGFR1, rs1838105 and in WNT9B) with NSOC in a Northern Chinese population....