Article
Association of single-nucleotide polymorphisms of CDH1 with nonsyndromic cleft lip with or without cleft palate in a northern Chinese Han population.
Medicine - 1 Feb 2017
Song Hongquan, Wang Xiaotong, Yan Jiaqun, Mi Na, Jiao Xiaohui, Hao Yanru, Zhang Wei, Gao Yuwei
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation among live births, and depends on race and ethnic background. The CDH1 gene plays a vital role in orofacial development. Our research was conducted to examine the association between 3 single-nucleotide polymorphisms in the CDH1 gene and NSCL/P. METHODS: Three single-nucleotide polymorphisms (rs16260,...
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