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Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants

30 Aug 2018

Abstract excerpt

BACKGROUND: Hepatic membrane transporters are involved in the transport of many endogenous and exogenous compounds, including drugs. We aimed to study the relation of age with absolute transporter protein expression in a cohort of 62 mainly fetus and newborn samples. METHODS: Protein expressions of BCRP, BSEP, GLUT1, MCT1, MDR1, MRP1, MRP2, MRP3, NTCP, OCT1, OATP1B1, OATP1B3, OATP2B1 and ATP1A1 were quantified...

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PMID: 30171984
DOI: 10.1016/j.ejps.2018.08.042

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