Article
Molecular Subtypes and Genomic Profile of Primary Central Nervous System Lymphoma.
Journal of neuropathology and experimental neurology - 1 Feb 2020
Bödör Csaba, Alpár Donát, Marosvári Dóra, Galik Bence, Rajnai Hajnalka, Bátai Bence, Nagy Ákos, Kajtár Béla, Burján Adrienn, Deák Beáta, Schneider Tamás, Alizadeh Hussain, Matolcsy András, Brandner Sebastian, Storhoff James, Chen Ning, Liu Mingdong, Ghali Nadeem, Csala Irén, Bagó Attila G, Gyenesei Attila, Reiniger Lilla
Abstract excerpt
Primary central nervous system lymphomas (PCNSL) are aggressive non-Hodgkin lymphomas affecting the central nervous system (CNS). Although immunophenotyping studies suggested an uniform activated B-cell (ABC) origin, more recently a spectrum of ABC and germinal center B-cell (GC) cases has been proposed, with the molecular subtypes of PCNSL still being a matter of debate. With the emergence of novel therapies...
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