Article
Loss of LDAH associated with prostate cancer and hearing loss.
Human molecular genetics - 15 Dec 2018
Currall Benjamin B, Chen Ming, Sallari Richard C, Cotter Maura, Wong Kristen E, Robertson Nahid G, Penney Kathryn L, Lunardi Andrea, Reschke Markus, Hickox Ann E, Yin Yanbo, Wong Garrett T, Fung Jacqueline, Brown Kerry K, Williamson Robin E, Sinnott-Armstrong Nicholas A, Kammin Tammy, Ivanov Andrew, Zepeda-Mendoza Cinthya J, Shen Jun, Quade Bradley J, Signoretti Sabina, Arnos Kathleen S, Banks Alexander S, Patsopoulos Nikolaos, Liberman M Charles, Kellis Manolis, Pandolfi Pier Paolo, Morton Cynthia C
Abstract excerpt
Great strides in gene discovery have been made using a multitude of methods to associate phenotypes with genetic variants, but there still remains a substantial gap between observed symptoms and identified genetic defects. Herein, we use the convergence of various genetic and genomic techniques to investigate the underpinnings of a constellation of phenotypes that include prostate cancer (PCa) and sensorineural...
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