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Article

The Polygenic Architecture of Human Diseases Affecting the Hair Follicle.

The Journal of investigative dermatology - 1 Mar 2026

Brinks Anna L, Needle Carli D, Perez Olivia D, Shapiro Jerry, Lo Sicco Kristen I, Occidental Michael A, Tsirigos Aristotelis, Petukhova Lynn

Abstract excerpt

Disorders affecting the hair follicle (HF) and pilosebaceous unit impose psychosocial and financial burdens on patients and may signal risk for other medical conditions. Human genetic studies help to identify key physiological mechanisms that govern health and are increasingly used to improve drug development. GWASs identify genetic variants that are common in the population and implicate disease mechanisms that...

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Identifiers

PMID: 41137822
DOI: 10.1016/j.jid.2025.09.012
PMCID: PMC13373509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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