Article
Analysis of Epistasis in Natural Traits Using Model Organisms.
Trends in genetics : TIG - 1 Nov 2018
Campbell Richard F, McGrath Patrick T, Paaby Annalise B
Abstract excerpt
The ability to detect and understand epistasis in natural populations is important for understanding how biological traits are influenced by genetic variation. However, identification and characterization of epistasis in natural populations remains difficult due to statistical issues that arise as a result of multiple comparisons, and the fact that most genetic variants segregate at low allele frequencies. In...
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