Article
Histone Deacetylase Inhibitors: A Therapeutic Key in Neurological Disorders?
24 Aug 2018
Abstract excerpt
Understanding the contribution of imbalance in protein acetylation levels and dysfunction of transcription to neurodegenerative diseases provides the rationale for the use of epigenetic modulators such as histone deacetylase (HDAC) inhibitors to combat neurodegenerative conditions. It is now widely recognized that various low-molecular weight HDAC inhibitors are broadly neuroprotective, preventing or delaying...
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