Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone deacetylases as targets for the treatment of human neurodegenerative diseases

1 Jan 2009

Abstract excerpt

Histone deacetylases (HDACs) are a family of proteins that play an important role in regulating transcription as well as the function of a variety of cellular proteins. While these proteins are expressed abundantly in the brain, little is known about their roles in brain function. A growing body of evidence suggests that HDACs regulate neuronal survival. Results from studies conducted in vertebrate and mammalian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholinesterase and Neurodegenerative Diseases
Share to Histone Deacetylase Inhibitors Research
Share to Nuclear Receptors and Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20072728
DOI: 10.1358/dnp.2009.9.1428871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone deacetylases as targets for the treatment of human neurodegenerative diseasesPMID 20072728Read ↗

Histone Deacetylase Inhibitors: A Therapeutic Key in Neurological Disorders?Semantic proximity Read ↗

Class IIA HDACs in the regulation of neurodegenerationSemantic proximity Read ↗

Understanding the Role of Histone Deacetylase and their Inhibitors in Neurodegenerative Disorders: Current Targets and Future PerspectiveSemantic proximity Read ↗

Epigenetics in Neurodegenerative Diseases: The Role of Histone DeacetylasesSemantic proximity Read ↗

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?Semantic proximity Read ↗

Histone Deacetylase Inhibition in Alzheimer’s Disease: Molecular Mechanisms, Therapeutic Potential, and Future PerspectivesSemantic proximity Read ↗

Multiple roles of HDAC inhibition in neurodegenerative conditionsSemantic proximity Read ↗

Targeting HDACs: A Promising Therapy for Alzheimer's DiseaseSemantic proximity Read ↗

Molecular targets of histone deacetylase inhibitors in neurodegeneration and neuroprotectionSemantic proximity Read ↗

Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditionsSemantic proximity Read ↗

HDACs in the Brain: From Chromatin Remodeling to Neurodegenerative DiseaseSemantic proximity Read ↗

Targeting Histone Deacetylases: A Novel Approach in Parkinson’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.