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Article

Histone deacetylases as targets for the treatment of human neurodegenerative diseases

1 Jan 2009

Abstract excerpt

Histone deacetylases (HDACs) are a family of proteins that play an important role in regulating transcription as well as the function of a variety of cellular proteins. While these proteins are expressed abundantly in the brain, little is known about their roles in brain function. A growing body of evidence suggests that HDACs regulate neuronal survival. Results from studies conducted in vertebrate and mammalian...

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Cholinesterase and Neurodegenerative Diseases
Histone Deacetylase Inhibitors Research
Nuclear Receptors and Signaling

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20072728
DOI: 10.1358/dnp.2009.9.1428871

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