Article
A chromosomal rearrangement in a P. falciparum histidine-rich protein gene is associated with the knobless phenotype.
Nature - 1 Jan 2000
Pologe L G, Ravetch J V
Abstract excerpt
The significant morbidity and mortality associated with Plasmodium falciparum malaria results, in part, from the sequestration of parasitized erythrocytes in postcapillary venules, which may protect the parasite from splenic clearance and contribute to the pathogenesis of cerebral malaria. This sequestration has been linked to the expression of parasite-induced knob structures on the surface of the infected...
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