Article
Plasmodium falciparum: CD36 dependent cytoadherence or rosetting of infected erythrocytes is modulated by knobs.
Cell adhesion and communication - 1 Dec 1994
Crandall I, Guthrie N, Demers D, Sherman I W
Abstract excerpt
A knobless (K-) line of the FCR-3 isolate of Plasmodium falciparum was obtained by gelatin flotation. Immunofluorescent staining and immunoblots indicated that both the K- line and the K+ (knobby) line from which it was derived contained similar forms of potentially adhesive modified band 3 protein. When the K+ and K- lines were assayed for their cytoadherent and rosetting abilities the K+ line showed a high...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, CD
- CD36 Antigens
- Cell Adhesion
- Erythrocyte Membrane
- Erythrocytes
- Microscopy, Electron, Scanning
- Phenotype
- Plasmodium falciparum
- Receptors, Cytoadhesin