Article

Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence

2021-03-11

Abstract excerpt

The pathology associated with malaria infection is largely due to the ability of infected human erythrocytes to adhere to a number of receptors on endothelial cells within tissues and organs. This phenomenon is driven by the export of parasite-encoded proteins to the host cell, the exact function of many of which is still unknown. Here we inactivate the function of one of these exported proteins, PFA66, a member o...

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Literature Corpus work: 58af43c2-825e-5c75-a373-30eed3e02a60
DOI: 10.1101/2021.03.11.434953

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