Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse.

BMC genomics - 29 Aug 2018

Rudra Pratyaydipta, Shi Wen J, Russell Pamela, Vestal Brian, Tabakoff Boris, Hoffman Paula, Kechris Katerina, Saba Laura

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that bind messenger RNAs and promote their degradation or repress their translation. There is increasing evidence of miRNAs playing an important role in alcohol related disorders. However, the role of miRNAs as mediators of the genetic effect on alcohol phenotypes is not fully understood. We conducted a high-throughput sequencing study to measure miRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Sequence Analysis, RNA
Share to Alcohol-Related Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bayes Theorem

Share to Genetic Predisposition to Disease

Share to MicroRNAs

Share to Models, Statistical

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 30157779
DOI: 10.1186/s12864-018-5004-3
PMCID: PMC6114181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse.PMID 30157779Read ↗

Insight into genetic regulation of miRNA in mouse brain.Semantic proximity Read ↗

Voluntary exposure to a toxin: the genetic influence on ethanol consumption.Semantic proximity Read ↗

The sequenced rat brain transcriptome--its use in identifying networks predisposing alcohol consumption.Semantic proximity Read ↗

Influence of sex on genetic regulation of "drinking in the dark" alcohol consumption.Semantic proximity Read ↗

A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission.Semantic proximity Read ↗

Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption.Semantic proximity Read ↗

Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains.Semantic proximity Read ↗

Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependenceSemantic proximity Read ↗

miRNA-regulated transcription associated with mouse strains predisposed to hypnotic effects of ethanol.Semantic proximity Read ↗

Alcohol sensitivity in Drosophila: translational potential of systems genetics.Semantic proximity Read ↗

Genome-level analysis of genetic regulation of liver gene expression networks.Semantic proximity Read ↗

Genetical genomic determinants of alcohol consumption in rats and humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.