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Article

Feedback regulation of TORC1 by its downstream effectors Npr1 and Par32.

Molecular biology of the cell - 1 Nov 2018

Varlakhanova Natalia V, Tornabene Bryan A, Ford Marijn G J

Abstract excerpt

TORC1 (target of rapamycin complex) integrates complex nutrient signals to generate and fine-tune a growth and metabolic response. Npr1 (nitrogen permease reactivator) is a downstream effector kinase of TORC1 that regulates the stability, activity, and trafficking of various nutrient permeases including the ammonium permeases Mep1, Mep2, and Mep3 and the general amino acid permease Gap1. Npr1 exerts its...

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Identifiers

PMID: 30156471
DOI: 10.1091/mbc.E18-03-0158
PMCID: PMC6249832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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