Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TORC1 effector kinase Npr1 fine tunes the inherent activity of the Mep2 ammonium transport protein.

Nature communications - 1 Jan 2014

Boeckstaens Mélanie, Llinares Elisa, Van Vooren Pascale, Marini Anna Maria

Abstract excerpt

The TORC1 complex controls cell growth upon integrating nutritional signals including amino-acid availability. TORC1 notably adapts the plasma membrane protein content by regulating arrestin-mediated endocytosis of amino-acid transporters. Here we demonstrate that TORC1 further fine tunes the inherent activity of the ammonium transport protein, Mep2, a yeast homologue of mammalian Rhesus factors, independently of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Cation Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutamine

Share to Methylamines

Share to Mutant Proteins

Share to Phosphoserine

Share to Protein Kinases

Share to Protein Structure, Secondary

Source

Identifiers

PMID: 24476960
DOI: 10.1038/ncomms4101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TORC1 effector kinase Npr1 fine tunes the inherent activity of the Mep2 ammonium transport protein.PMID 24476960Read ↗

Feedback regulation of TORC1 by its downstream effectors Npr1 and Par32.Semantic proximity Read ↗

Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional SignalsSemantic proximity Read ↗

Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae.Semantic proximity Read ↗

Alpha-arrestins Aly1 and Aly2 regulate intracellular trafficking in response to nutrient signaling.Semantic proximity Read ↗

Yeast α-arrestin Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters.Semantic proximity Read ↗

TORC1 signaling is governed by two negative regulators in fission yeast.Semantic proximity Read ↗

CPK28-mediated phosphorylation enhances nitrate transport activity of NRT2.1 during nitrogen deprivation.Semantic proximity Read ↗

Target of rapamycin complex 1 and Tap42-associated phosphatases are required for sensing changes in nitrogen conditions in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Who does TORC2 talk to?Semantic proximity Read ↗

Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway.Semantic proximity Read ↗

Manganese is a Physiologically Relevant TORC1 Activator in Yeast and MammalsSemantic proximity Read ↗

Nitrogen source activates TOR (target of rapamycin) complex 1 via glutamine and independently of Gtr/Rag proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.