Article
T Cell Abnormalities in X-Linked Agammaglobulinaemia: an Updated Review.
Clinical reviews in allergy & immunology - 1 Aug 2023
Chawla Sanchi, Jindal Ankur Kumar, Arora Kanika, Tyagi Rahul, Dhaliwal Manpreet, Rawat Amit
Abstract excerpt
X-linked agammaglobulinaemia (XLA) is a primary immunodeficiency (PID) resulting from a defect in the B cell development. It has conventionally been thought that T cells play a major role in the development and function of the B cell compartment. However, it has also been shown that B cells and T cells undergo bidirectional interactions and B cells also influence the structure and function of the T cell...
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