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Article

Relationship of genetic determinants of height with cardiometabolic and pulmonary traits in the Hispanic Community Health Study/Study of Latinos.

International journal of epidemiology - 1 Dec 2018

Sofer Tamar, Moon Jee-Young, Isasi Carmen R, Qi Qibin, Shah Neomi A, Kaplan Robert C, Kuniholm Mark H

Abstract excerpt

Background: Associations of adult height with cardiometabolic and pulmonary traits have been studied in majority European ancestry populations using Mendelian randomization and polygenic risk score (PRS) analysis. The standard PRS approach entails creating a PRS for height using variants identified in prior genome-wide association studies (GWAS). It is unclear how well the standard PRS approach performs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30137430
DOI: 10.1093/ije/dyy177
PMCID: PMC6280956

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