Article
No association of DNM3 with age of onset in Asian Parkinson's disease.
European journal of neurology - 1 May 2019
Foo J N, Tan L C, Au W-L, Prakash K-M, Liu J, Tan E-K
Abstract excerpt
BACKGROUND AND PURPOSE: Genetic variability in DNM3 has been shown to modify age of onset of Parkinson's disease (PD) among LRRK2 Gly2019Ser carriers in North African Arab-Berber populations. In Asian populations, the Gly2019Ser mutation is rare or absent but two other LRRK2 variants, Gly2385Arg and Arg1628PPro, increase PD risk. We aimed to determine whether the DNM3 locus was associated with age of PD onset in...
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