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Mitochondrial NADH Dehydrogenase Subunit 3 Polymorphism Associated with an Earlier Age at Onset in Male Machado-Joseph disease Patients.

CNS neuroscience & therapeutics - 1 Jan 2016

Chen Sheng, Gan Shi-Rui, Cai Ping-Ping, Ni Wang, Zhou Qi, Dong Yi, Wang Ning, Wu Zhi-Ying

Abstract excerpt

AIMS: To investigate the potential effect of six previously reported candidate single nucleotide polymorphisms on age at onset (AAO) among Chinese patients with Machado-Joseph disease (MJD). METHODS: Three hundred and twenty-four unrelated molecular-confirmed MJD patients were recruited between January 2006 and December 2014. The screening of candidate polymorphisms was first performed in 173 subjects using the...

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PMID: 26336829
DOI: 10.1111/cns.12443
PMCID: PMC6492796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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