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Article

Alzheimer's genetic risk is reduced in primary age‐related tauopathy: a potential model of resistance?

19 Jun 2018

Abstract excerpt

Abstract Objective Nearly all adults >50 years of age have evidence for neurofibrillary tau tangles ( NFT s) and a significant proportion of individuals additionally develop amyloid plaques (A β ) consistent with Alzheimer's disease ( AD ). In an effort to identify the independent genetic risk factors for NFT s and A β , we investigated genotypic frequencies of AD susceptibility loci between autopsy‐confirmed...

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PMID: 30128317
DOI: 10.1002/acn3.581

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