Article
Fragmentation of the Golgi Apparatus in Neuroblastoma Cells Is Associated with Tau-Induced Ring-Shaped Microtubule Bundles.
Journal of Alzheimer's disease : JAD - 1 Jan 2018
Rodríguez-Cruz Fanny, Torres-Cruz Francisco Miguel, Monroy-Ramírez Hugo Christian, Escobar-Herrera Jaime, Basurto-Islas Gustavo, Avila Jesús, García-Sierra Francisco
Abstract excerpt
Abnormal fibrillary aggregation of tau protein is a pathological condition observed in Alzheimer's disease and other tauopathies; however, the presence and pathological significance of early non-fibrillary aggregates of tau remain under investigation. In cell and animal models expressing normal or modified tau, toxic effects altering the structure and function of several membranous organelles have also been...
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