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Article

Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death.

Journal of the neurological sciences - 15 Jul 2006

Gonatas Nicholas K, Stieber Anna, Gonatas Jacqueline O

Abstract excerpt

Fragmentation of the neuronal Golgi apparatus (GA) was reported in amyotrophic lateral sclerosis (ALS), corticobasal degeneration, Alzheimer's and Creutzfeldt-Jacob disease, and in spinocerebelar ataxia type 2 (SCA2). In transgenic mice expressing the G93A mutant of Cu/Zn superoxide dismutase (SOD1) of familial ALS (fALS), fragmentation of the GA of spinal cord motor neurons and aggregation of mutant protein were...

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Source

Identifiers

PMID: 16545397
DOI: 10.1016/j.jns.2006.01.019

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death.PMID 16545397Read ↗

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Establishment of a cell model of ALS disease: Golgi apparatus disruption occurs independently from apoptosis.Semantic proximity Read ↗

Fragmentation of the Golgi apparatus induced by the overexpression of wild-type and mutant human tau forms in neurons.Semantic proximity Read ↗

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