Article
Positive selection for elevated gene expression noise in yeast.
Molecular systems biology - 1 Jan 2009
Zhang Zhihua, Qian Wenfeng, Zhang Jianzhi
Abstract excerpt
It is well known that the expression noise is lessened by natural selection for genes that are important for cell growth or are sensitive to dosage. In theory, expression noise can also be elevated by natural selection when noisy gene expression is advantageous. Here we analyze yeast genome-wide gene expression noise data and show that plasma-membrane transporters show significantly elevated expression noise...
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