Article
Correlations between T-cell specificity and the structure of the antigen receptor.
Nature - 1 Jan 2000
Fink P J, Matis L A, McElligott D L, Bookman M, Hedrick S M
Abstract excerpt
The derived amino-acid sequences of the heterodimeric antigen receptors expressed by a series of murine T-cell clones are presented. A comparison of the receptor sequences indicates that several mechanisms for generating receptor diversity can influence T-cell specificity, including junctional diversity, combinatorial joining, and combinatorial chain associations.
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