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Article

Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans.

Archives of oral biology - 1 Nov 2018

Funato Noriko, Yanagisawa Hiromi

Abstract excerpt

OBJECTIVE: We examined the function of the T-box transcription factor 1 (TBX1) in palatogenesis. DESIGN: Tbx1-knockout mice were histologically examined by hematoxylin and eosin staining. Next, secondary palatal shelves dissected from wild type or Tbx1-knockout mice embryos at embryonic day 13.5 were investigated with microarray analysis, gene ontology analysis, and real-time quantitative polymerase chain...

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Source

Identifiers

PMID: 30121012
DOI: 10.1016/j.archoralbio.2018.08.001

Genes

TBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans.PMID 30121012Read ↗

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