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Article

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function.

BMC genomics - 4 Jun 2018

Zoupa Maria, Xavier Guilherme Machado, Bryan Stephanie, Theologidis Ioannis, Arno Matthew, Cobourne Martyn T

Abstract excerpt

BACKGROUND: Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate. Amongst the genes within this region, TBX1 is a major candidate for many of these developmental defects. Targeted deletion of Tbx1 in the mouse has provided significant insight into the function of this transcription...

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Source

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Identifiers

PMID: 29866044
DOI: 10.1186/s12864-018-4782-y
PMCID: PMC5987606

Genes

TBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene expression profiling in the developing secondary palate in the absence of Tbx1 function.PMID 29866044Read ↗

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