Article
Curcumin reduces Ly6Chi monocyte infiltration to protect against liver fibrosis by inhibiting Kupffer cells activation to reduce chemokines secretion.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2018
Zhao Xiang-An, Chen Guangmei, Liu Yong, Chen Yuxin, Wu Hongyan, Xiong Yali, Wang Guiyang, Jia Bei, Li Yang, Xia Juan, Wang Jian, Yan Xiaomin, Zhang Zhaoping, Huang Rui, Wu Chao
Abstract excerpt
Curcumin has been reported to have anti-fibrotic effect. However, the anti-fibrotic mechanism of curcumin for liver fibrosis remains obscure. In the presenting study, we aimed to investigate whether curcumin reduce chemokines secretion by inhibiting kupffer cells (KCs) activation to decrease Ly6Chi monocyte infiltration in the treatment of liver fibrosis. Liver fibrosis was induced by intraperitoneal carbon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.