Article
Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure.
Journal of translational medicine - 6 Mar 2014
Zhang Min, Ye Yinong, Wang Fenglan, Zhu Jianyun, Zhao Qiyi, Zheng Yubao, Gu Yurong, Xie Chan, Huang Zhanlian, Tai Qiang, Chong Yutian, Gao Zhiliang
Abstract excerpt
BACKGROUND: Although patients with liver failure exhibit a generalized inflammatory-imbalance status, substantial evidence indicates that this immunosuppressive or anti-inflammatory state may be deleterious. Increased expression of CD163 (known to be involved in several anti-inflammatory functions of the immune system) in patients with liver failure is significantly correlated with a fatal outcome. However,...
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