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Article

Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism

16 Aug 2018

Abstract excerpt

Antibiotics lead to increased susceptibility to colonization by pathogenic organisms, with different effects on the host-microbiota relationship. Here, we show that metronidazole treatment of specific pathogen-free (SPF) mice results in a significant increase of the bacterial phylum Proteobacteria in fecal pellets. Furthermore, metronidazole in SPF mice decreases hind limb muscle weight and results in smaller...

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PMID: 30115857
DOI: 10.3390/ijms19082418

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