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The Response of the Rodent Gut Microbiome to Broad-Spectrum Antibiotics Is Different in Males and Females

9 Jun 2022

Abstract excerpt

Gut microbiome composition is different in males and females, but sex is rarely considered when prescribing antibiotics, and sex-based differences in gut microbiome recovery following antibiotic treatment are poorly understood. Here, we compared the effects of broad-spectrum antibiotics on both the stool and small bowel microbiomes in male and female rats. Adult male and female Sprague Dawley rats were exposed to...

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PMID: 35756061
DOI: 10.3389/fmicb.2022.897283

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