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Characterization of avian influenza virus attachment patterns to human and pig tissues

9 Aug 2018

Abstract excerpt

Wild birds of Anseriformes and Charadriiformes are natural reservoirs of influenza A viruses (IAVs). Occasionally, IAVs transmit and adapt to mammalian hosts, and are maintained as epidemic strains in their new hosts. Viral adaptions to mammalian hosts include altered receptor preference of host epithelial sialylated oligosaccharides from terminal α2,3-linked sialic acid (SA) towards α2,6-linked SA. However,...

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PMID: 30111851
DOI: 10.1038/s41598-018-29578-1

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