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Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host

9 Aug 2018

Abstract excerpt

Malaria parasites transmitted by mosquito bite are remarkably efficient in establishing human infections. The infection process requires roughly 30 minutes and is highly complex as quiescent sporozoites injected with mosquito saliva must be rapidly activated in the skin, migrate through the body, and infect the liver. This process is poorly understood for Plasmodium vivax due to low infectivity in the in vitro...

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PMID: 30111801
DOI: 10.1038/s41598-018-30713-1

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