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Human leukocyte antigen (HLA) typing by DNA sequencing.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Lazaro Ana, Tu Bin, Yang Ruyan, Xiao Yi, Kariyawasam Kanthi, Ng Jennifer, Hurley Carolyn Katovich

Abstract excerpt

DNA sequencing is a powerful technique for identifying allelic variation within the human leukocyte antigen (HLA) genes. Sequencing is usually focused on the most polymorphic exons of the class I (HLA-A, -B, -C) and class II (HLA-DR, -DQ, and -DP) genes. These exons encode the antigen recognition site, the region of the HLA molecule that binds peptides and interacts with the T cell receptor for antigen and...

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PMID: 23775737
DOI: 10.1007/978-1-62703-493-7_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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